HOUSTON (AP) — Travis Wood hit a three-run homer and pitched shutout ball into the seventh inning to lead the Cincinnati Reds to a 6-1 win over the Houston Astros on Monday night.

Wood’s shot to the Crawford Boxes in left field made it 3-0 in the third inning and Ramon Hernandez pushed the lead to 5-0 with a two-run homer to almost the same spot an inning later.

Wood (2-3) allowed six hits and struck out six with a walk in 6 2/3 innings for his first win since April 2, his first start of the season.

The Reds looked to have figured out Houston starter Aneury Rodriguez just five days after they managed just one hit in five scoreless innings against him in his first major league start.

Rodriguez (0-1) allowed five runs and eight hits in five innings.

He received a no-decision in last week’s start against the Reds after closer Brandon Lyon blew the save in a 3-2 Houston loss.

Hunter Pence tripled in the first and scored Houston’s only run with a solo homer in the eighth inning.

The Reds extended the lead to 6-0 with a two-out, RBI single by Drew Stubbs in the sixth inning.

Wood’s homer was the second of his career and the first by a Reds pitcher since he hit his first one in September off Adam Wainwright of the Cardinals. A double by Chris Valaika followed by Ryan Hanigan’s single set up the three-run homer. Hanigan finished with three hits.

Hernandez’s third homer of the season came after Fred Lewis led off the inning with a single to right field.

Wood had retired six straight when Clint Barmes singled with one out in the fifth inning. Pinch hitter Matt Downs singled after that, but Wood retired the next two to end the inning.

He pitched a perfect sixth before he was chased with a single by Angel Sanchez with two outs in the seventh. Wood walked Brett Wallace to start that inning and got some help from Brandon Phillips when he robbed Chris Johnson of a hit with a nifty diving catch that ended in a belly flop for the first out.

Reliever Bill Bray gave up a single to Michael Bourn to load the bases before he was replaced by Logan Ondrusek, who retired J.R. Towles to end the inning.

Pence tripled with two outs in the first inning, but Carlos Lee struck out to end that threat.

Cincinnati’s Mike Leake, who was moved to the bullpen from the rotation when Homer Bailey came off the disabled list last week, pitched a perfect ninth in his first relief appearance of the season.

NOTES: Reds manager Dusty Baker gave 1B Joey Votto the day off. … Houston manager Brad Mills said he expects Lyon’s stint on the disabled list to stretch longer than 15 days. He went on the disabled list on Thursday with tendinitis in his biceps and a partial tear in his rotator cuff, which can heal without surgery. Mills said after the swelling subsides, it will take some time for him to build back his arm strength enough to return

Reds 6, Astros 1

Cincinnati Houston

ab r h bi ab r h bi

Stubbs cf 5 0 2 1 Bourn cf 5 0 2 0

Renteri ss 4 0 0 0 Towles c 4 0 0 0

Bruce rf 4 0 0 0 Pence rf 4 1 2 1

BPhllps 2b 4 0 2 0 Ca.Lee lf 4 0 1 0

FLewis lf 4 1 1 0 Hall 2b 3 0 1 0

Ondrsk p 0 0 0 0 Wallac 1b 3 0 0 0

JGoms ph 1 0 0 0 CJhnsn 3b 4 0 0 0

Leake p 0 0 0 0 Barmes ss 4 0 1 0

RHrndz 1b 5 1 1 2 AnRdrg p 1 0 0 0

Valaika 3b 4 2 2 0 MDwns ph 1 0 1 0

Hanign c 4 1 3 0 Figuero p 0 0 0 0

T.Wood p 3 1 1 3 AngSnc ph 1 0 1 0

Bray p 0 0 0 0 JValdz p 0 0 0 0

Heisey lf 1 0 0 0 Bogsvc ph 1 0 0 0

Totals 39 6 12 6 Totals 35 1 9 1

Cincinnati 003 201 000 — 6

Houston 000 000 010 — 1

E—Wallace (2). DP—Cincinnati 1. LOB—Cincinnati 9, Houston 9. 2B—Valaika (1), Hall (4). 3B—Pence (1). HR—R.Hernandez (3), T.Wood (1), Pence (5). SB—Renteria (1).

IP H R ER BB SO

Cincinnati

T.Wood W,2-3 6 2-3 6 0 0 1 6

Bray 0 1 0 0 0 0

Ondrusek 1 1-3 2 1 1 0 0

Leake 1 0 0 0 0 1

Houston

An.Rodriguez L,0-1 5 8 5 5 1 3

Figueroa 2 3 1 1 2 3

J.Valdez 2 1 0 0 0 3

Bray pitched to 1 batter in the 7th.

HBP—by Ondrusek (Hall).

Umpires—Home, Brian Runge; First, Tim McClelland; Second, Marvin Hudson; Third, Ted Barrett.

T—3:02. A—20,174 (40,963).